Overall survival with adjuvant pembrolizumab in renal cell carcinoma — the shock of the lightning

Nature Reviews Urology, Published online: 17 May 2024; doi:10.1038/s41585-024-00896-6In the KEYNOTE-564 trial, patients with resected clear cell renal cell carcinoma at a high risk of relapse experienced disease-free survival and especially overall survival benefits following treatment with pembrolizumab, which in turn was established as the novel standard adjuvant therapy for these patients. Accurate patient selection is crucial. Managing post-pembrolizumab recurrence is challenging owing to limited evidence for guiding therapeutic decisions based on clinical features.

Posted on: 16 May 2024 | 7:00 pm

Promoting the health of men of all backgrounds: educating ourselves to build trust and improve care

Nature Reviews Urology, Published online: 16 May 2024; doi:10.1038/s41585-024-00893-9Specific issues affect the treatment of urological cancer and survivorship in gay and bisexual men. Creating an accepting and inclusive environment for these patients in our men’s health clinics can help to improve the quality of life for men from sexual minority groups undergoing cancer treatment.

Posted on: 15 May 2024 | 7:00 pm

AUA24 — pioneering shared decision-making and patient engagement strategies

Nature Reviews Urology, Published online: 15 May 2024; doi:10.1038/s41585-024-00898-4AUA24 — pioneering shared decision-making and patient engagement strategies

Posted on: 14 May 2024 | 7:00 pm

Chromosome segregation in SCNT oocytes

Nature Reviews Urology, Published online: 14 May 2024; doi:10.1038/s41585-024-00895-7Chromosome segregation in SCNT oocytes

Posted on: 13 May 2024 | 7:00 pm

Overcoming barriers in cancer care for gender minorities

Nature Reviews Urology, Published online: 13 May 2024; doi:10.1038/s41585-024-00894-8As the population of gender minorities grows in the setting of rising incidence of cancers globally, health-care professionals and institutions must be prepared to provide inclusive care. Individual-level training as well as institutional-level efforts on gender identity data collection and creation of inclusive clinical spaces could help mitigate health-care disparities.

Posted on: 12 May 2024 | 7:00 pm

Centralization of care for rare genetic syndromes associated with cancer: improving outcomes and advancing research on VHL disease

Nature Reviews Urology, Published online: 08 May 2024; doi:10.1038/s41585-024-00874-yIn this Perspective, Larcher et al. describe a dedicated treatment programme for Von Hippel–Lindau disease established at San Raffaele Hospital, which encompasses diagnosis, surveillance, treatment, research and outreach. The authors then discuss the benefits of care centralization for Von Hippel–Lindau disease and other rare diseases.

Posted on: 7 May 2024 | 7:00 pm

We all get erections — de-gendering sexual arousal dysfunction in the ICD

Nature Reviews Urology, Published online: 08 May 2024; doi:10.1038/s41585-024-00890-yDefinitions of sexual arousal dysfunction in the International Classification of Diseases use sex-specific binaries that omit the erectile basis of arousal in females. To provide equitable health care for all people with erectile dysfunction, these definitions must be de-gendered.

Posted on: 7 May 2024 | 7:00 pm

Asexuality: the invisible orientation

Nature Reviews Urology, Published online: 07 May 2024; doi:10.1038/s41585-024-00891-xAsexuality is often neglected in education and conversations around sexuality, making it essentially an ‘invisible orientation’. This lack of knowledge is associated with harmful misconceptions, which need challenging within the medical profession and in the general population to ensure inclusion of people who identify on the asexual spectrum.

Posted on: 6 May 2024 | 7:00 pm